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Lab Test

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Lyme IgG and IgM

Lyme Antibody (IgG/IgM), Lyme Ab, Lyme Antibody, IgG/IgM, Lyme Antibody, IgG and IgM

Test Codes

EPIC: LAB6896, SOFT: LYME

Department

Special Chemistry

Specimen Collection Criteria

Collect: One Gold-top SST tube. (Minimum Whole Blood: 6.0 mL)

Physician Office/Draw Specimen Preparation

Let specimen clot 30-60 minutes then immediately centrifuge to separate serum from cells. Refrigerate (2-8°C or 36-46°F) the centrifuged collection tube within two hours of collection. (Minimum Serum: 1.5 mL)

Preparation for Courier Transport

Transport: Centrifuged collection tube, refrigerated (2-8°C or 36-46°F). (Minimum Serum: 1.5 mL)

Rejection Criteria

Plasma specimens.

Severely lipemic, icteric, or hemolyzed specimens.  

In-Lab Processing

Let specimen clot 30-60 minutes then immediately centrifuge to separate serum from cells. Room temperature is acceptable for a maximum of two hours. (Minimum Serum: 1.5 mL)

Storage

Specimen Stability for Testing:

Centrifuged SST Tubes and Microtainers® with Separator Gel
Room Temperature (20-26°C or 68-78.8°F): 8 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): Unacceptable

Red-top Tubes and Microtainers® without Separator Gel
Room Temperature (20-25°C or 68-77°F): 8 hours
Refrigerated (2-8°C or 36-46°F): Unacceptable
Frozen (-20°C/-4°F or below): Unacceptable

Serum Specimens (Pour-Overs)
Room Temperature (20-26°C or 68-78.8°F): 8 hours
Refrigerated (2-8°C or 36-46°F): 7 days
Frozen (-20°C/-4°F or below): 1 year

Specimen Storage in Department Prior to Disposal:

Refrigerated (2-8°C or 36-46°F): 7 days

Laboratory

Royal Oak Special Testing Laboratory

Performed

Tuesday, Friday.
Results available within 3 business days.

Reference Range

Units: Index Value (IV).
Negative: Less than or equal to 0.89.
Equivocal: 0.90-1.09.
Positive: Greater than or equal to 1.10. 

Test Methodology

Chemiluminescent Immunoassay. Measures IgG and IgM antibodies to VIsE (variable major protein-like sequence, expressed) protein antigen of Borrelia burgdorferi in human serum.

Interpretation

A negative test result indicates that both IgG and IgM are negative. A positive test result indicates that IgG, IgM, or both are positive. All positive and equivocal results are sent out for Lyme Immunoblot testing. Prompt antibiotic treatment can interfere with specific antibody responses.

Clinical Utility

This assay aids in the diagnosis of infection with B. burgdorferi.

CPT Codes

86618
LOINC:  6320-6

Contacts

Last Updated

7/29/2021

Microtainer® and Vacutainer® are registered trademarks of Becton, Dickinson and Company.
UroVysion® is a registered trademark of Abbott Laboratories. ThinPrep® is a registered trademark of Hologic, Incorporated.