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Amoxapine Level and Metabolite

Asendin, Amoxapine and Metabolite

Test Codes

NMS: 0325, Antrim #80250, EPIC: LAB5939, SOFT: XAMOX

Specimen Collection Criteria

Collect (preferred specimen): One plain Red-top tube.
Also Acceptable: One Lavender-top EDTA tube.

Do not use Serum Separator Tubes.
Time of Collection: Trough, just prior to the next dose.

Physician Office/Draw Specimen Preparation

Centrifuge to separate serum or plasma from cells within two hours of collection. Transfer serum or plasma to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Preparation for Courier Transport

Transport: 1.0 mL serum or plasma at refrigerated (2-8°C or 36-46°F). (Minimum: 0.3 mL)

Rejection Criteria

• Serum Separator (SST) tubes.
• Specimens not collected or processed as indicated.

In-Lab Processing

Centrifuge to separate serum or plasma from cells within two hours of collection. Transfer serum or plasma to a plastic transport tube and refrigerate (2-8°C or 36-46°F).

Transport: 2.0 mL serum or plasma, refrigerated (2-8°C or 36-46°F). (Minimum: 0.7 mL) 

Storage

Ambient: 14 days
Refrigerated: 14 days
Frozen: 10 months

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT, forwarded to National Medical Services (NMS), Willow Grove, PA.

Performed

Varies.
Results available in 4-10 days.

Reference Range

By report.

Test Methodology

Quantitative High Performance Liquid Chromatography / Tandem Mass Spectrometry.

Interpretation

By report.

Clinical Utility

Amoxapine is an antidepressant. This assay is used for the therapeutic monitoring and toxicity assessment of amoxapine. 8-hydroxyamoxapine is an active metabolite and is reported to assist interpretation of amoxapine drug levels.

CPT Codes

80335 (alternate: G0480).

Contacts

Last Updated

4/10/2021