Fibrin Split Products
FSP, FDP, Fibrin Breakdown products
Test Codes
Antrim #26175, EPIC: LAB5188
Instructions
Collection tubes can be obtained by contacting the Laboratory:
- Grosse Pointe: 313-473-1809
- Royal Oak: 248-551-8084
- Troy: 248-964-8040
- Outreach: 1-800-511-0488
Specimen Collection Criteria
Collect: 2.0 mL whole blood into a special tube provided in the Burroughs Wellcome Thrombo-Wellco test kit. Send to coagulation department immediately.
Each tube contains Bothrops venom to ensure complete clotting of fibrinogen and a fibrinolytic inhibitor to prevent breakdown of fibrin in vitro.
Physician Office/Draw Specimen Preparation
Allow specimen to clot for 30-60 minutes at room temperature (20-26°C or 68-78.8°F). Centrifuge to separate serum from cells immediately after clotting. Transfer serum into plastic transport tube and freeze (-20°C/-4°F or below). Place specimen on DRY ICE prior to transport. Specimens must be received in the Laboratory within 6 hours of collection.
Preparation for Courier Transport
Transport: Serum in plastic transport tube, frozen (-20°C/-4°F or below).
Rejection Criteria
Specimens that are not collected in the special Thrombo-Wellco tubes.
Specimens containing less than 0.5 mL.
In-Lab Processing
Allow specimen to clot for 30-60 minutes at room temperature (20-26°C or 68-78.8°F). Centrifuge to separate serum from cells immediately after clotting. Transfer serum into plastic transport tube and freeze (-20°C/-4°F or below) prior to testing.
Storage
Specimen Stability for Testing:
Room Temperature (20-26°C or 68-78.8°F): 6 hours
Refrigerated (2-8°C or 36-46°F): Unacceptable
Frozen (-20°C/-4°F or below): Serum aliquot must be frozen for transport.
Specimen Storage in Department Prior to Disposal:
Room Temperature (20-26C or 68-78.8F): 7 days
Refrigerated (2-8°C or 36-46°F): 7 days
Laboratory
Dearborn Hematology Laboratory
Royal Oak Coagulation Laboratory
Taylor Hematology Laboratory
Trenton Hematology/Coagulation Laboratory
Troy Hematology/Coagulation Laboratory
Wayne Hematology/Coagulation Laboratory
Performed
Sunday – Saturday, 24 hours a day.
STAT results available within 30 minutes of receipt in the Laboratory.
Routine results available within 4 hours of receipt in the Laboratory.
Reference Range
Normal Value: Less than 10 mcg/mL.
Test Methodology
Latex Agglutination (Thrombo-Wellco).
Interpretation
- Fibrin split products are elevated in DIC.
- This test is not specific for Fragments D and E but will also react with fibrinogen, FSP (X, Y, D and E) and fibrin monomer.
Clinical Utility
- Fibrin(ogen) split products are formed by digestion of fibrin(ogen) as a result of activation of the fibrinolytic system.
- This test aids in the detection of DIC.
- This test is not to be used for the exclusion of deep vein thrombosis (DVT) or pulmonary embolism (PE).
CPT Codes
85362
Contacts
Hematology Laboratory – TYL
313-295-5360
Name: Hematology Laboratory – TYL
Location:
Phone: 313-295-5360
Hematology Laboratory – DBN
313-593-7905
Name: Hematology Laboratory – DBN
Location:
Phone: 313-593-7905
Hematology/Coagulation Laboratory – TRN
734-671-3862
Name: Hematology/Coagulation Laboratory – TRN
Location:
Phone: 734-671-3862
Hematology/Coagulation Laboratory – WYN
734-467-4274
Name: Hematology/Coagulation Laboratory – WYN
Location:
Phone: 734-467-4274
Coagulation Laboratory – RO
248-551-8084
Name: Coagulation Laboratory – RO
Location:
Phone: 248-551-8084
Hematology/Coagulation Laboratory – TR
248-964-8040
Name: Hematology/Coagulation Laboratory – TR
Location:
Phone: 248-964-8040
Last Updated
12/17/2021
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