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Pyridostigmine

Mestinon, Regonol, Pyridostigmine (Mestinon)

Test Codes

NMS #4038SP, Order as a Miscellaneous Send Out.

Specimen Collection Criteria

Collect (preferred specimen): Two plain Red-top tubes.
Also acceptable: Three Lavender-top EDTA tubes.

Do not use Serum Separator Tubes.
Critical frozen. Send specimen for processing immediately after collection.

Physician Office/Draw Specimen Preparation

Critical Frozen. Centrifuge to separate serum or plasma from cells. Transfer serum or plasma to a plastic transport tube and freeze (-20°C/-4°F or below) immediately.

Preparation for Courier Transport

Transport: 5.0 mL serum or plasma, frozen (-20°C/-4°F or below). (Minimum: 2.2 mL)

Rejection Criteria

Serum Separator (SST) tubes.

Specimens not collected and processed as indicated. 

In-Lab Processing

Critical Frozen. Centrifuge to separate serum or plasma from cells. Transfer serum or plasma to a plastic transport tube and freeze (-20°C/-4°F or below) immediately.

Transport: 5.0 mL serum or plasma, frozen (-20°C/-4°F or below). (Minimum: 2.2 mL)

Storage

Specimen Stability for Testing:

Room Temperature (20-26°C or 68-78.8°F): Unacceptable
Refrigerated (2-8°C or 36-46°F): Unacceptable
Frozen (-20°C/-4°F or below): 3 weeks

Specimen Storage in Department Prior to Disposal:

Specimen retention time is determined by the policy of the reference laboratory. Contact the Send Outs Laboratory with any questions.

Laboratory

Sent to ARUP Laboratories, Salt Lake City, UT, forwarded to National Medical Services (NMS), Willow Grove, PA.

Performed

Wednesday.
Results available in 4-11 days.

Reference Range

By report.

Test Methodology

Gas Chromatography.

Interpretation

By report.

Clinical Utility

Pyridostigmine (Mestinon) is an orally active cholinesterase inhibitor. Mestinon is useful in the treatment of myasthenia gravis. This assay is used for the therapeutic monitoring and toxicity assessment of pyridostigmine.

CPT Codes

80375

Contacts

Last Updated

4/10/2021